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Innovative research treatment for cancer patients undergoing surgery for prevention of cancer recurrence and prevention of cancer metastasis

חדשות 12 14.10.21
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The study is intended for patients prior to surgery.

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The treatment is intended to prevent metastatic development, which may be accelerated around the time of surgery.

The treatment is based on existing and safe medications that are marketed in Israel and internationally, and are given for a short period around the time of surgery.

This treatment reduces inflammatory responses and activity of the sympathetic nervous system and has been scientifically proven to be effective in animal and human studies.

 

The research is a collaboration between Tel Aviv University and medical centers, is a non-profit organization and is not affiliated with pharmaceutical companies.

The treatment is provided free of charge and does not replace existing treatments.

Treatment begins 5 days before surgery and continues several weeks afterward.

צרי/ צור קשר

A comprehensive explanation of our research

המחקרים שלנו

Active studies

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Completed studies

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צוות החוקרים

The research team

Prof. Shamgar Ben-Eliyahu

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Prof. Shamgar Ben-Eliyahu heads the Neuroimmunology Research Laboratory at the School of Neuroscience at Tel Aviv University, and was previously head of the Department of Psychology. Prof. Ben-Eliyahu has been studying the relationship between surgery to remove a primary cancer tumor and the appearance of metastases and recurrence of the disease. Prof. Ben-Eliyahu is also developing drug treatments designed to reduce the impact of stress hormones and inflammation on the weakening of the immune system and the establishment and development of cancer metastases.

Prof. Oded Zamora

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Prof. Oded Zmora is the director of the surgical departments at Shamir Medical Center (formerly Assaf Harofeh Hospital). Prof. Zmora is a specialist in general surgery, colorectal surgery, which combines intestinal surgery, and proctology, which treats diseases of the rectum. Prof. Zmora is a graduate of the Hebrew University School of Medicine in Jerusalem. He completed his general surgery residency at Sheba Medical Center in Tel Hashomer and Mount Sinai Medical Center in New York. After completing his residency, Prof. Zmora specialized in colorectal surgery at the Cleveland Clinic in Florida, one of the world's leading centers in this field.

In addition to Prof. Ben Eliyahu and Prof. Zamora, doctors, nurses, and research coordinators at the hospitals participating in the study are taking part in this study

עיתונות ופרסומים מדעיים

The scientific background to the research

We have developed a drug treatment based on existing, safe, and inexpensive drugs (Darlin and Etofen – or their generic names: propranolol and etodolac) that blocks the unwanted effects of inflammatory and stress factors. In animal studies, we have shown, in six different types of cancer, that these drug treatments given around the time of surgery prevents metastases and saves lives after removal of the primary cancerous tumor. In humans, we have already conducted two small studies that have shown the safety of the treatment and promising results at the level of the cancer tissue and the prevention of bowel cancer recurrence after five years.

We are now testing the treatment on a large scale in several medical centers, with the goal of showing that it will prevent recurrence of metastases after surgery and save lives.

Journalism and scientific publications

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מחקר ישראלי פורץ דרך:

תרופות קיימות וזולות

הצליחו למנוע משמעותית

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INVESTIGADORES ISRAELÍES

DESCUBRIERON TRES

FÁRMACOS COMUNES

QUE PUEDEN REDUCIR

EL RIESGO DE METÁSTASIS

TRAS UN CÁNCER

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Des chercheurs israéliens

ont découvert trois médicaments

courants susceptibles

de réduire le risque

de métastases après un cancer

du côlon ou du rectum
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For more information and to participate in the study, fill out the compatibility form.

Research to prevent cancer metastasis | Tel Aviv University | Shamir Medical Center   

Hadassah Ein Kerem Medical Center | Hasharon Medical Center | Iichilov Medical Center | Sheba Medical Center | Assuta medical Center | Wolfson Medical Center

 

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